Permission granted to use by
Taxonomic ClassificationLamiaceae family
Rosmarinus officinalis L. had been used in traditional systems of medicine throughout the world, including Traditional Chinese Medicine, derives from its use in ancient Greek medicine. Rosemary leafs contains contain 20-30 different monoterpenes with antifungal and antimicrobial activity. Rosemary is grown specifically for its diterpenoid carnosic acid, which is used as an anti-oxidant. Carnosic acid (CA) can protect the brain from stroke and neurodegeneration that is due to injurious chemical free radicals. Studies have shown that carnosic acid also stimulates Nerve Growth Factor (NGF) synthesis and may be a treatment modality for Alzheimer's disease. Pentacyclic triterpenes of rosemary included betulinic acid, a very promising new chemotherapeutic agent for the treatment of HIV infection and cancer; ursolic acid stopped the movement of all T. cruzi epimastigotes at the minimum concentration (MC100) of 40mg/ml (88mM) after 48 h of incubation. A multitude of biological activities have been described for phenylpropanoid rosmarinic acid. Main activities are adstringent, antioxidative, antiinflammatory, antimutagen, antibacterial and antiviral.
|Chemical Structure: Betulinic acid||Clinical Trials||Major Metabolites|
|Enzyme Name||EC No||Genbank Accession||GI No|
aThe Total Entries column is the sum of the entries from the dbEST, dbGSS, dbPLN, and dbHTG columns. Data retrieved from NCBI on May 14 2010.